diethylene glycol monobutyl ether toxicity

Glycol is a chemical compound that is diol containing two hydroxyl groups. Ektasolve DB acetate. Comparative toxicity studies with three glycol ethers, 2-methoxyethanol, 2-ethoxyethanol, and 2-butoxyethanol, … Salmonella (401459) Completed . Google Scholar. Superlist … Diethylene glycol monobutyl ether for synthesis Synonym: Butyl carbitol, 2-(2-Butoxyethoxy) ethanol, Butyl diglycol, Diethylene glycol monobutyl ether CAS Number 112-34-5. Solvant de produits organiques, fabrication de produits organiques. kajohnson@dow.com Standard toxicologic endpoints, supplemented by … 2,2'-OXYBIS- ETHANOL, 2,2'-OXYBISETHANOL, 2,2'-OXYDIETHANOL, BIS(2-HYDROXYETHYL)ETHER, DIETHYLENE GLYCOL, DIGLYCOL, ETHANOL, 2,2 OXYBIS, and ETHANOL, 2,2'-OXYBIS-Cancer . It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. NSC 5175. DGBE was administered dermally at 10 or 30% v/v in aqueous solutions or undiluted (100%) for 13 weeks under occlusion, 6 hr/day, 5 days/week at a maximum attainable volume of 2 mL/kg. Both ethylene glycol and diethylene glycol are produced from same starting material; ethylene. 3.8 Toxicity by Inhalation: Currently not available. 2-(2-Butoxyethoxy)ethyl acetate. Objectives The solvent, dimethylene glycol monobutyl ether (DGBE), is a component of latex paints, inks; it is used as a degreasing agent, industrial detergent. 9 Citations. EPA reviewed the available human health toxicity data and aquatic ecological toxicity data for EGBE and concluded that it can reasonably be anticipated to cause serious or … The difference between ethylene glycol and diethylene glycol is that an ethylene glycol molecule is an individual molecule whereas diethylene glycol molecule is formed by the combination of two ethylene glycol molecules via an ether bond. 3 Altmetric. In a clinical setting, most commonly encountered glycol is ethylene glycol. MDL number MFCD00002881. Production and Use. DPM Solvant dipropylene glycol monomethyl ether - CAS N° 34590-94-8. Satellite groups of male and female … The subchronic and reproductive toxicity of diethylene glycol butyl ether (DGBE) by the dermal route was evaluated in Sprague-Dawley rats using a novel combined protocol. Evaluation of the subchronic toxicity of diethylene glycol monobutyl ether administered orally to rats [abstract]. Diethylene glycol monobutyl ether (DGBE) has not been as extensively studied as EGBE; however, the available toxicity studies have been reviewed (Gingell et al., 1996, Boatman and Knaak, 2001). Diethylene glycol monomethyl ether (diEGME) was one of 15 glycols tested in CD-1 mice using a short-term in vivo reproductive toxicity assay (Chernoff/Kavlock test). Propriétés physiques 1 2. Diethylene Glycol Monobutyl Ether (>95%) 112-34-5: Liquid >480 > indicates greater than. Acute and Subchronic Toxicity of Ethylene Glycol Monobutyl Ether by Tipton R. Tyler* The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Toxicologist 1986;6:659. Serged and bound seams are degraded by some hazardous liquid chemicals, such as strong acids, and should not be worn when these chemicals are present. Diglycol monobutyl ether acetate. EINECS 204-685-9. Liquide hygroscopique, incolore à odeur fruitée. It can also serve as a dispersant in organosols and can also be used in preparation of plasticizers. Grand choix parmi 10 Kit complet béton ciré (1). Livraison rapide partout en France. DGME is also used as a deicer … Return to footnote 10 referrer. Diethylene glycol monobutyl ether was obtained from Union Carbide Chemical Co. as Butyl Carbitol, Lot #S767216. EPA has denied a petition to remove Ethylene Glycol Monobutyl Ether (EGBE) from the list of chemicals subject to reporting under section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA). Glycol ether DB aceatate . Acute oral toxicity of ethylene glycol monomethyl ether and diethylene glycol monomethyl ether. DEG is a widely used solvent. Salmonella Mutagenicity Test The plate incorporation mutagenicity assay with and without an Aroclor-induced Sprague-Dawley rat liver S-9 fraction was performed as described by Ames et al. Three additional structural analogs are included to support this category. Author information: (1)Department of Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI 48674, USA. EPA/OTS Doc #: 86-890001170S. Liquide transparent, incolore à odeur caractéristique. Linear Formula HOCH 2 CH 2 OCH 2 CH 2 O(CH 2) 3 CH 3. Molecular Weight 162.23 . Provisional Peer-Reviewed Toxicity Values for Diethylene Glycol Monomethyl Ether (CASRN 111-77-3) ... Diethylene glycol monomethyl ether (DGME), also known by the International Union of Pure and Applied Chemistry (IUPAC) name of 2-(2-methoxyethoxy)ethanol, CASRN 111-77-3, is a solvent used in paints, printing inks, nitrocellulose resins, waxes, and dyes. … It is miscible in water, alcohol, ether, acetone, and ethylene glycol. diethylene glycol monobutyl ether ethanol diethylene glycol dimethyl ether triethylene glycol dimethyl ether propylene glycol monomethyl ether propylene glycol monomethyl ether acetate dipropylene glycol dipropylene glycol monomethyl ether A. bbreviation EGME EGMEA EGEE EGEEA EGPE EGBE EGDME EGDEE DEG DEGME DEGE DEGBE DEGDME TEGDME PGME PGMEA … This website and underlying databases are maintained and updated by Pesticide Action Network North America (PAN). A blank cell indicates the fabric has not been tested. Developmental & Reproductive Toxicity . Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. Diethylene glycol (DEG) (CAS 111-46-6) is listed in the Inventory with functions as solvent, viscosity controlling and masking/perfuming. Propriétés physiques 1. NTIS/OTS0520310. Diethylene glycol monoethyl ether; Utilisation et sources d'émission . UNII-U6UTS77LXB. Mise à jour : 1994-03-24. … Johnson KA, Baker PC, Kan HL, Maurissen JP, Spencer PJ, Marty MS. Diethylene glycol monobutyl ether (DGBE): two and thirteen-week oral toxicity studies in Fisher 344 rats. Diethylene glycol monomethyl ether - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information: Note: See Working with the Information on this Page section below for important notes about this data. Diethylene glycol hexyl ether is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). CASRN: 112-34-5 Formula: C8-H18-O3 Synonyms/Common Names. 14. Mise à jour : 2009-08-19. These studies included absorption and elimination of dermally applied doses Packaging 1, 4 L in poly bottle 18 L in steel drum Legal Information Product of Dow Chemical Diethylene glycol, monobutyl ether, acetate. Other less frequently encountered glycols include diethylene glycol, propylene glycol, ethylene glycol monobutyl ether (EGBE), and ethylene glycol monomethyl ether (EGME). Caractéristiques. Biodegradation of diethylene glycol hexyl ether may take place based on a study using pure culture Pseudomonas sp 4-5-3 which degraded diethylene glycol hexyl ether … … In July 2007 the Spanish authorities informed the Commission services about their findings of DEG in concentrations as high as 7-8.3% in toothpaste products. Mise à jour : 2003-06-06. A preliminary toxicity assay was performed with strain … 79 Accesses. EC Index Number 203-961-6 Ethanol, 2-(2-butoxyethoxy)-, 1-acetate. Footnote 11. 3.9 Chronic Toxicity: Currently not available 3.10 Vapor (Gas) ... DIETHYLENE GLYCOL MONOBUTYL ETHER DME 9.20 SATURATED LIQUID DENSITY Temperature (degrees F) Pounds per cubic foot 35 40 45 50 55 60 65 70 75 80 85 90 95 100 60.410 60.280 60.150 60.020 59.890 59.760 59.630 59.500 59.370 59.240 59.110 58.980 58.850 … Hygiène et sécurité Apparence 1. Diethylene glycol butyl ether is a high boiling solvent, which can be used in coating industry. Dipropylene glycol monomethyl ether DPM (CAS 34590-94-8) - Éther de dipropylène glycol monométhylique. Fabrication de produits organiques, solvant de produits organiques Hygiène et sécurité Apparence . Diethylene glycol monobutyl ether; Utilisation et sources d'émission. Ethylene glycol monomethyl ether (EGME) and its acetate ester (EGMEA) are highly flammable, colorless, moderately volatile liquids with very good solubility properties. 106 THOMPSON ET AL. (Concise international chemical assessment document ; 41) 1.Ethylene glycols - adverse effects 2.Ethylene glycols - toxicity 3.Methyl ethers - adverse effects 4.Methyl ethers - toxicity 5.Risk assessment 6.Environmental exposure I.International Programme on Chemical Safety II.Series The aim of the study was evaluating the effects of DGBE administered by gavage on the estrous cycle and given with drinking water on fertility in rats and early development of their progeny. Diethylene glycol butyl ether (2-(2-Butoxyethoxy)ethanol) is an organic compound, one of several glycol ether solvents. Diethylene Glycol is an aliphatic diol. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Testing Status of Diethylene glycol monobutyl ether 11139-J . Johnson KA(1), Baker PC, Kan HL, Maurissen JP, Spencer PJ, Marty MS. Diethylene glycol monobutyl ether agent detailed information in Haz-Map database. Diethylene glycol monobutyl ether (DGBE): two- and thirteen-week oral toxicity studies in Fischer 344 rats. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. The site is secure. The fabric may or may not offer barrier. Toshihiro Kawamoto 1, Koji Matsuno 1, Fujio Kayama 1, Manabu Hirai 2, Kelichi Arashidani 2, Masahiro Yoshikawa 2 & Yasushi Kodama 1 Bulletin of Environmental Contamination and Toxicology volume 44, pages 602 – 608 (1990)Cite this article. Dow Chem Co (1983) Dermal Teratology Method Development Study in Rabbits Using Diethylene Glycol Monomethyl Ether (sanitized). However, for aquatic toxicity, diethylene glycol ethers (DGEE, DGPE and DGHE) and diethylene glycol ether acetates (DGEEA and DGBEA) are considered separately because diethylene glycol ether acetates do not hydrolyze readily in water at environmental conditions. It is mainly used as a solvent for paints and varnishes in the chemical industry, household detergents, brewing chemicals and textile processing. Food Chem Toxicol 2005;43:467–481. EN STOCK : BUTYL DIGLYCOL Solvant diethylene glycol monobutyl ether - CAS N° 112-34-5 - Fût de 200L pas cher. Furthermore, it is listed in section II, perfume and aromatic raw materials. Diethylene glycol dimethyl ether. HSDB 334. Because results were strongly suggestive of potential reproductive toxicity, a teratology study was conducted in Sprague-Dawley rats. Ethanol, 2-(2-butoxyethoxy)-, acetate. Synonyms Ethylene Glycol Monobutyl Ether, Butyl Cellosolve* 8 ETHYLENE GLYCOL ETHERS, NTP TOXICITY REPORT NUMBER 26 Glycol alkyl ethers represent a class of high-production-volume chemicals with widespread industrial applications as solvents and chemical intermediates. 2-(2-Butoxyethoxy)ethanol ; Genetic Toxicology. Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. Systematic Names. The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. OF DIETHYLENE GLYCOL MONOBUTYL ETHER (DGBE) IN RATS KRYSTYNA SITAREK, JOLANTA GROMADZIŃSKA, PIOTR LUTZ, JAN STETKIEWICZ, RADOSŁAW ŚWIERCZ, and WOJCIECH WĄSOWICZ Nofer Institute of Occupational Medicine, Łódź, Poland Department of Toxicology and Carcinogenesis Abstract Objectives: The solvent, dimethylene glycol monobutyl ether (DGBE), is a … Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Couleur / Aspect: incolore: Odeur: caractéristique: Densité : 0,955: Point Eclair: 105°C: Point d'ébullition: 230°C: N° CAS: 112-34-5: À voir également. 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